Glucovance 5 Mg-500 Mg Tablet: Uses, Side Effects


Glucovance 5 Mg-500 Mg Tablet is a medication commonly prescribed to manage type 2 diabetes mellitus. It combines two active ingredients, glyburide and metformin, which work together to help control blood sugar levels. In this article, we will explore the uses, potential side effects, and other important information about Glucovance.


1. Uses of Glucovance 5 Mg-500 Mg Tablet

Glucovance is primarily prescribed to individuals with type 2 diabetes. It is not intended for the treatment of type 1 diabetes or diabetic ketoacidosis. Here are the key uses of Glucovance:

A. Blood Sugar Control: The primary purpose of Glucovance is to lower and control blood sugar levels in people with type 2 diabetes. It achieves this by two different mechanisms of action.

B. Enhancing Insulin Sensitivity: Metformin, one of the active ingredients, improves the body’s sensitivity to insulin, making it more effective in regulating blood sugar.

C. Stimulating Insulin Release: Glyburide stimulates the pancreas to release more insulin, further aiding in blood sugar control.

2. Dosage and Administration

The dosage of Glucovance 5 Mg-500 Mg Tablet is determined by a healthcare provider and tailored to the individual patient’s needs. It is usually taken orally with meals to reduce the risk of gastrointestinal side effects. Patients should strictly adhere to their prescribed dosage and not adjust it without consulting their healthcare provider.

3. Possible Side Effects

Glucovance Like any medication, Glucovance can have side effects, although not everyone will experience them. Common side effects may include:

A. Gastrointestinal Issues: Nausea, diarrhea, and stomach upset are relatively common side effects when starting Glucovance. These symptoms often improve over time.

B. Hypoglycemia: Since Glucovance increases insulin production, it can lead to low blood sugar levels (hypoglycemia). Symptoms include shakiness, sweating, irritability, and confusion. It’s essential to monitor blood sugar levels closely and have a plan for managing low blood sugar episodes.

C. Weight Gain: Some individuals may experience weight gain while taking Glucovance.

D. Skin Reactions: Rarely, Glucovance can cause skin reactions, such as itching or a rash. If you notice any skin changes, contact your healthcare provider.

E. Lactic Acidosis: Although rare, metformin (one of Glucovance’s components) can lead to a severe condition called lactic acidosis, characterized by symptoms like muscle pain, weakness, and breathing difficulties. Seek immediate medical attention if you experience these symptoms.

4. Precautions and Contraindications

Certain individuals should exercise caution or avoid Glucovance altogether. It is important to inform your healthcare provider if you:

  • Have kidney or liver problems.
  • Are pregnant or planning to become pregnant.
  • Are breastfeeding.
  • Have a history of alcohol abuse.
  • Have had allergic reactions to medications containing glyburide or metformin.

To get accurate and up-to-date pricing information for Glucovance 5 Mg-500 Mg Tablet or any other medication, I recommend the following steps:

  1. Contact a Local Pharmacy: You can call or visit your local pharmacy and ask for the current price of the medication. Pharmacies often have pricing information readily available.
  2. Check Online Pharmacy Websites: Many online pharmacies provide pricing information for medications. You can visit their websites and search for Glucovance to compare prices.
  3. Use Prescription Discount Cards: Some prescription discount card programs offer savings on medications. You can search for these programs online or inquire at your pharmacy.
  4. Consult Your Insurance Provider: If you have health insurance, contact your insurance provider to inquire about your coverage for Glucovance. They can provide information on your copay or coinsurance.
  5. Ask Your Healthcare Provider: Your doctor or healthcare provider may also have information about the cost of Glucovance and may be able to recommend cost-effective alternatives if needed.

Remember that medication prices can fluctuate, so it’s a good idea to compare prices from multiple sources and explore any available discounts or assistance programs to help reduce your out-of-pocket costs. Additionally, always consult with your healthcare provider before making any changes to your medication regimen.

5. Conclusion

Glucovance 5 Mg-500 Mg Tablet is a valuable medication for managing type 2 diabetes by controlling blood sugar levels. It combines the actions of glyburide and metformin to help improve insulin sensitivity and stimulate insulin release. While it is generally safe and effective, it is essential to be aware of potential side effects and follow your healthcare provider’s guidance closely. Always consult with your doctor before starting or discontinuing any medication, including Glucovance.

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